His career began in 1984, when he graduated from the College of Medicine, University of Lagos. He completed his postgraduate training at the University College Hospital, Ibadan in 1994 where he bagged the award of Fellowship of the West African College of Surgeons in Obstetrics and Gynaecology.

He joined Lagoon Hospital, Apapa in 1995 as an Obstetrics & Gynaecology Consultant and held the post for 7 years. During his stay, Dr. Ajayi was appointed the coordinator of the out-patient services of the Hospital.

He also served as a part-time medical consultant to several clinics and blue chip organizations such as Chevron and Texaco Nigeria Plc, Lagos.

In 2003, he started Nordica Fertility Centre in Lagos, pioneering a wide range of assisted reproduction services across the nation. The clinic specializes in In-Vitro Fertilization (IVF) and treatment of infertility for couples facing fertility challenges in marriages and has since inception expanded into 2 other major cities in Nigeria – Abuja and Asaba. It is also an affiliate of Nordica, Denmark.Driven by passion to help enhance the quality of medical service in his country, Dr. Ajayi went further to train at the Iscare Centre for Assisted Reproduction, Bratislava, Slovak Republic; The Institute of Human Reproduction Symbion, Fruebjerguej and The Fertility Clinic of Copenhagen University, Herlev Hospital, both in Copenhagen, Denmark.He also established a platform called the ‘Physicians Roundtable’ where doctors can network and stay abreast of latest breakthroughs in fertility management and reproductive technology.